Introduction
Powder for concentrate for solution for infusion Brentuximab vedotin
Treat classical Hodgkin lymphoma
- Adcetris (Brentuximab vedotin) is indicated for treatment of patients with Hodgkin lymphoma
(HL) after failure of autologous stem cell transplant (ASCT) or after failure of at least two prior
multi-agent chemotherapy regimens in patients who are not ASCT candidates. - Adcetris is indicated for treatment of patients with systemic anaplastic large cell lymphoma(sALCL) after failure of at least one prior multi-agent chemotherapy regimen.
Warning & Precautions
Talk to Doctor
Talk to your doctor before you take this medicine, if you:
Pregnancy & Breast Feeding
Brentuximab vedotin should not be used during pregnancy unless the benefit to the mother outweighs the potential risks to the foetus. If a pregnant woman needs to be treated she should be clearly advised on the potential risk to the foetus.
There are no data as to whether brentuximab vedotin or its metabolites are excreted in human milk. A risk to the newborn/infant cannot be excluded. A decision should be made whether to discontinue breast-feeding or to discontinue/abstain from this therapy, taking into account a potential risk of breast-feeding for the child and the benefit of therapy for the woman.
Driving & Using Machines
Brentuximab vedotin may have a minor influence on the ability to drive and use machines.
Interactions
Tell your doctor if you are taking,
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How to Use
This medicine is given to you into a vein (intravenously) as an infusion. It is given by your doctor or
nurse over 30 minutes. Your doctor or nurse will also monitor you during and after the infusion.
Side Effects
Like all medicines, this medicine can cause side effects, although not everybody gets them
- Peripheral neuropathy
- Anaphylaxis and Infusion Reactions
- Hematologic Toxicities
- Serious Infections and Opportunistic Infections
- Tumor Lysis Syndrome
- Increased Toxicity in the Presence of Severe Renal Impairment
- Increased Toxicity in the Presence of Moderate or Severe Hepatic Impairment
- Hepatotoxicity
- Progressive Multifocal Leukoencephalopathy
- Serious Dermatologic Reactions
- Embryo-Fetal Toxicity
More Information
Disclaimer:
The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.