IntroductionWhat SYNDOPA PLUS is used for?
- SYNDOPA PLUS improves the signs of Parkinson’s disease
Warning & PrecautionsTalk to Doctor
Talk to your doctor before you take this medicine, if you:
- Are allergic (hypersensitive) to carbidopa or levodopa or any of the other ingredients of SYNDOPA PLUS
- Have ever had skin cancer or you have any unusual moles which have not been examined by your doctor
- Have a condition called ‘narrow-angle glaucoma’ that may cause a sudden buildup of pressure in the eye
- Have a history of fits (convulsions)
- Have had an ulcer in your gut (called ‘duodenal’ or ‘peptic ulcer’) or have vomited blood
- Have had a heart attack, heart beat problems, circulation or breathing problems
- Have had kidney, liver or hormonal problems
- Have had depression or other mental problems
- Have a condition called ‘chronic wide-angle glaucoma’ that may cause a buildup of pressure in the eye
- Sometimes have sudden sleep attacks or sometimes feel very sleepy
Pregnancy & Breast Feeding
- It is unknown whether SYNDOPA PLUS will pass into human milk
- Ask your doctor for advice before taking any medicine, if you are pregnant or planning to become pregnant or are breast-feeding
Children & Adolescents
- SYNDOPA PLUS is not suitable for children under the age of 18 years
Driving & Using Machines
- SYNDOPA PLUS can also make you sleepy or cause "sudden sleep attacks". If this happens to you, you must not drive or use tools or machines
- Do not drive or use tools or machines if you get these effects your doctor will tell you if you can start driving again if these attacks stop
InteractionsTell your doctor if you are taking,
- Medicines for Parkinson’s disease containing levodopa
- Medicines for mental problems (including depression), tuberculosis (TB), high blood pressure, muscle spasms, epilepsy or other diseases related to involuntary movements
- Iron supplements
- Fluoxetine
- Orphenadrine, trihexyphenidyl, benzatropine and procyclidine (anticholinergic agents)
- Medicines used to treat fits such as carbamazepine
- Papaverine which is used to treat impotence in men
How to Use- Always take SYNDOPA PLUS exactly as your doctor has told you
- Take this medicine by mouth
- Although your medicine can have an effect after one day, it may take up to seven days to work
- Take them at regular time intervals according to your doctor"s instructions
- Do not change the times at which you take your tablets or take any other medicines for Parkinson"s disease without first consulting your doctor
- Try to avoid taking your tablets with a heavy meal
- Reduce/avoid a high-protein diet (e.g. meat, poultry, and dairy products) while you are taking the medicine as it can reduce the amount of medication absorbed by your body.
- Be cautious?while driving or doing anything that requires concentration as Syndopa Plus Tablet can make you very sleepy.
- When you start the medication, get out of bed slowly, as the medication may cause dizziness, lightheadedness or fainting.
- Do not stop taking the medication without talking to your doctor. It may result in a serious syndrome that causes fever, stiff muscles, unusual body movements, sweating, and confusion.
- Talk to your doctor in case you develop hallucinations or other changes in your behavior.
If you take more SYNDOPA PLUS
- If you take too many tablets, see your doctor immediately
If you forget to take SYNDOPA PLUS
- Do not take a double dose to make up for a forgotten dose
If you stop taking?SYNDOPA PLUS
- Do not stop taking SYNDOPA PLUS without talking to your doctor first
Side EffectsLike all medicines, this medicine can cause side effects, although not everybody gets them
Serious
- Allergic reaction, the signs may include hives (nettle rash), itching, and rash, swelling of your face, lips, tongue or throat
- Breathing or swallowing
- Chest pain
- Irregular heart beat or palpitations
- Dizziness on standing-up quickly
- Bleeding from your gut which may be seen as blood in your faeces or darkened faeces (gastro-intestinal bleeding)
- Blood problems, the signs may include pale skin (pallor), tiredness, fever, sore throat or mild bruising and prolonged bleeding after injury
- Stiff muscles, high fever
- Mental changes including delusions, hallucinations and depression
- Fits (convulsions)
Common
- Abnormal movements such as twitching or spasms (which may or may not be like your Parkinson"s symptoms)
- Nausea
Uncommon
- Fainting, anorexia, high blood pressure
- Inflammation of the veins, being sick (vomiting) diarrhoea, discoloration of urine, sweat or saliva
- Dream abnormalities, confusion, feeling agitated, shortness of breath, hair loss
Rare
- Severe abnormal involuntary movements (dyskinesia’s), mood swings
- Strong impulse to gamble excessively despite serious personal or family consequences
- An increased sexual drive
- Uncontrollable excessive shopping or spending
- Binge eating (eating large amounts of food in a short time period) or compulsive eating (eating more food than normal and more than is needed to satisfy your hunger)
HOW TO COPE WITH SIDE EFFECTS?
The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.
Coping with Nausea and Vomiting
You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
Coping with Headache
Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. Ask your doctor to recommend a painkiller if they last longer than a week or get worse.
More InformationAdditional Information
- You become slow and unsteady
- Your muscles feel stiff
- You may develop shaking or trembling (called ‘tremor’)
Storage
- Keep this medicine out of reach of children
- Store at room temperature (15-25°C)
- Do not use this medicine after the expiry date
FAQsSyndopa is a combination of two medicines: Levodopa and Carbidopa. This medication is used to treat the symptoms of Parkinson"s disease like tremors (shaking), stiffness and slowness of movement. These symptoms are caused due to the lack of dopamine, a natural substance usually found in the brain. Levodopa works by being converted to dopamine in the brain. Carbidopa works by preventing levodopa from being broken down before it reaches the brain. By increasing the amount of dopamine in the brain, Syndopa helps control the symptoms of Parkinson’s disease and helps you to perform daily activities such as dressing, walking, handling utensils, etc.
Q. Can I stop taking Syndopa when my symptoms are relieved?
No, you should continue to take Syndopa, even if you feel well. Do not stop taking Syndopa without talking to your doctor. If you suddenly stop taking Syndopa, you could develop a serious problem causing fever, rigid muscles, unusual body movements and confusion. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.
Q. Can the Syndopa cause sleepiness or drowsiness?
Syndopa may make you drowsy or may cause you to suddenly fall asleep during your daily activities. You might not feel drowsy or notice any other warning signs before suddenly falling asleep. Avoid driving a car, operating machinery, working at heights or participating in potentially dangerous activities at the beginning of your treatment until you know how the medication affects you. If you suddenly fall asleep while doing something such as watching television, talking, eating, or riding in a car, or if you become very drowsy, especially during the daytime, call your doctor.
Q. Can the Syndopa cause dark urine?
Yes, the consumption Syndopa may alter the colour of your saliva, urine or sweat and make it dark colored (red, brown or black). This is harmless but your clothing may become stained.
Q. What are the instructions for storage and disposal of Syndopa?
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Q. How long does Syndopa take to cure Parkinson’s disease?
Syndopa controls Parkinson"s disease but does not cure it. It may take several months before you feel the full benefit of Syndopa.
Q. Can I take a higher than the recommended dose of this medication?
No, taking a higher than the recommended dose of Syndopa can lead to increased chances of side effects and toxicity. Talk to your doctor if your symptoms do not improve after a few weeks of treatment. Also let your doctor know if the effects of this medication seem to wear off quickly in between doses.
Disclaimer:The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.
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The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.